Coluracetam

Product Name: Coluracetam
CAS No.: 135463-81-9
Chemical Name: Coluracetam
Synonyms: BCI-540;COLURACETAM;Colurac tam;MKC-231;BCI-540;Coluracetam, >=99%;Coluracetam, MKC-231;COLURACETAM USP/EP/BP;top quality Coluracetam;MKC-231; MKC231; MKC 231;CAS135463-81-9 COLURACETAM
CBNumber: CB62446491
Molecular Formula: C19H23N3O3
Formula Weight: 341.4
MOL File: 135463-81-9.mol

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Coluracetam Property

Boiling point:: 634.1±55.0 °C(Predicted)
Density: 1.291±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMF: 1 mg/ml; DMSO: 2 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): insol
form: A crystalline solid
pka: 12.01±0.20(Predicted)
InChI: InChI=1S/C19H23N3O3/c1-11-12(2)25-19-17(11)18(13-6-3-4-7-14(13)20-19)21-15(23)10-22-9-5-8-16(22)24/h3-10H2,1-2H3,(H,20,21,23)
InChIKey: PSPGQHXMUKWNDI-UHFFFAOYSA-N
SMILES: N1(CC(NC2C3=C(N=C4OC(C)=C(C)C4=2)CCCC3)=O)CCCC1=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

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N-Bromosuccinimide Price

ChemScene

Product number: CS-2196
Product name: Coluracetam
Purity: 99.87%
Packaging: 10mg
Price: $60
Updated: 2021/12/16

ApexBio Technology

Product number: B1158
Product name: Coluracetam
Packaging: 10mg
Price: $79
Updated: 2021/12/16

ChemScene

Product number: CS-2196
Product name: Coluracetam
Purity: 99.87%
Packaging: 50mg
Price: $80
Updated: 2021/12/16

ChemScene

Product number: CS-2196
Product name: Coluracetam
Purity: 99.87%
Packaging: 5mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-2196
Product name: Coluracetam
Purity: 99.87%
Packaging: 100mg
Price: $90
Updated: 2021/12/16

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Coluracetam Chemical Properties,Usage,Production

Uses

Copiracetam can be used as a nootropic drug to treat memory and intellectual impairments caused by senile dementia, mild to moderate vascular dementia, trauma and other diseases, and to promote children's intellectual development; it also has antidepressant effects.

Pharmacology

Copiracetam has the ability to improve cognition by participating in the HACU process, increasing the rate-limiting step of synaptic intake of choline to synthesize the neurotransmitter acetylcholine, and increasing the activity of cholinergic neurons.

in vitro

Coluracetam (10(-10)-10(-6) moll), also known as MKC-231, significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding.

in vivo

Oral administration of MKC-231 (Coluracetam; 1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested.

Coluracetam Preparation Products And Raw materials

Raw materials

Preparation Products

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Coluracetam Suppliers

China 197 Europe 1 India 2 Japan 1 United States 11 Global 212

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2784
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63711
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

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View Lastest Price from Coluracetam manufacturers

Shanghai Affida new material science and technology center

Product: Coluracetam 135463-81-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 10 tons
Release date: 2024-04-26

Wuhan Haorong Biotechnology Co.,Ltd

Product: COLURACETAM 135463-81-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000
Release date: 2023-08-11

Wuhan Cell Pharmaceutical Co., Ltd

Product: Coluracetam 135463-81-9
Price: US $2.00-1.50/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2023-04-11

135463-81-9, ColuracetamRelated Search:

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COLURACETAM

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1-Pyrrolidineacetamide,2-oxo-N-(5,6,7,8-tetrahydro-2,3-dimethylfuro[2,3-b]quinolin-4-yl)-

Coluracetam, MKC-231

1-[N-(2,3-DiMethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)carbaMoylMethyl]pyrrolidin-2-one

BCI-540

Coluracetam, >=99%

2-oxo-N-(5,6,7,8-tetrahydro-2,3-dimethyl-furo[2,3-b]quinolin-4-yl)-1-pyrrolidineacetamide

coluracetam cas: 135463-81-9

MKC-231;BCI-540

MKC-231; MKC231; MKC 231

top quality Coluracetam

COLURACETAM USP/EP/BP

CAS135463-81-9 COLURACETAM

Furo(2,3-b)quinoline-1-pyrrolidineacetamide Deriv

COLURACETAM MKC-231 BCI-540

Colurac tam

135463-81-9

Brain health drug

Nootropic

pharmaceutical intermediate or medicine grade

pharmaceutical